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Printable Version Santyl

Active Ingredients: Collagenase
Other Names: Collagenase Ointment, Santyl
Product Images & Descriptions:

What is/are Santyl?
What should I tell my health care providers before I take this medicine?
How should I use this medicine?
What if I miss a dose?
What may interact with this medicine?
What side effects may I notice from this medicine?
What should I watch for while using this medicine?
Where should I keep this medicine?

What is/are Santyl? (Back to top)
COLLAGENASE is an enzyme that breaks down collagen in damaged tissue and helps healthy tissue to grow. This medicine may help wounds heal faster. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.


What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

  • an unusual or allergic reaction to collagenase, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine? (Back to top)
This medicine is for external use only. Do not take by mouth. Wash the wound as directed by your health care professional. Do not scrub. If you are applying a topical antibiotic to the wound, apply the antibiotic before this medicine. Do not touch the tip of the ointment tube with any surface, especially your fingers or the wound. Try to only get the ointment on the wound itself. If some gets on normal skin, wipe away with a sterile gauze pad. Do not use your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.


What if I miss a dose? (Back to top)
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.


What may interact with this medicine? (Back to top)
Do not take this medicine with any of the following:

  • aluminum acetate, Burow's solution
  • povidone iodine
  • silver nitrate
  • silver sulfadiazine

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.


What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

  • breathing problems
  • skin rash or hives

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
  • redness at the application site

This list may not describe all possible side effects.


What should I watch for while using this medicine? (Back to top)
Visit your doctor or health care professional for regular checks on your progress. If your wound begins to look worse, smell bad, has colored discharge or more discharge, or increases in size, contact your health care professional. You may have an infection or need a change in your treatment.

If you develop a fever, chills, low blood pressure, dizziness, rapid heartbeat, or confusion, contact your health care professional immediately. You may have an infection of your blood.


Where should I keep this medicine? (Back to top)
Keep out of the reach of children.

Store below 25 degrees C (77 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.


Last Updated:July 10, 2006

COPYRIGHT© Gold Standard, An Elsevier Company


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.

  Additional Information

  Check Drug Interactions with Santyl

  Test Yourself! If you currently take Santyl, do you know everything that you need to know?

  Make your own printable Medication / Emergency Contact Card



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